You can set breakpoints in the Add Breakpoint dialog box, which you open from the Debug menu in the main window. You can view a list of breakpoints currently set in your program in the Breakpoints pane in the Debugger window.
For instructions on setting a breakpoint, see:
Setting a Breakpoint on a LineFor instructions on removing a breakpoint, see:
Setting a Breakpoint on a Method Name
Setting a Breakpoint on an Exception
Setting a Breakpoint on a Class
Setting a Breakpoint on a Thread
Setting a Breakpoint on a Variable
Setting a Conditional Breakpoint
Disabling a Breakpoint
Removing a Breakpoint